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Participant Basic Agreement (PBA) Opportunity - Threat Agnostic Host-Directed Therapeutics

DEPT OF DEFENSENAICS 541714

Agency

DEPT OF DEFENSE

Location

—

Estimated Value

N/A

Type

Special Notice

Service / NAICS

541714

Opportunity Summary

This federal contract opportunity from DEPT OF DEFENSE involves participant basic agreement (pba) opportunity - threat agnostic host-directed therapeutics.

Contract Description

1. Strategic Opportunity: The Capability Program Executive for Chemical, Biological, Radiological, and Nuclear Defense (CPE CBRND) invites interested parties to participate in the HEALER portfolio, a next-generation host directed medical countermeasure initiative. HEALER seeks to develop a diverse portfolio of threat agnostic, host-directed therapeutics that enhance the body’s ability to withstand, mitigate, and recover from the complex physiological impacts of CBRN threats. Because the underlying pathophysiology of injury following CBRN exposure and civilian critical care challenges are often governed by convergent host response mechanisms, this program creates a viable commercial opportunity that exceeds the traditional CBRN mission space. This initiative represents a significant opportu...

Timeline

Posted Date

Apr 23, 2026

Should You Pursue This?

Good Fit If…

  • ✓You have worked with DEPT OF DEFENSE before

Harder to Win If…

  • !Full and open competition — no set-aside restrictions

Related Context

Agency

DEPT OF DEFENSE

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NAICS Code

541714

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Contractor FAQ

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To bid on this opportunity, you must be registered in SAM.gov. Review the full solicitation documents available at SAM.gov, prepare your technical and cost proposals per the instructions, and submit before the response deadline.

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Original listing: View on SAM.gov

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